BDBM163632 SR-3297::US10807944, Compound RLS2-219::US11731934, Compound RLS2-219

SMILES Brc1ccc(cc1)C(=O)NNCCC1CCCC1

InChI Key InChIKey=ZLEUBTRYAAACNU-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 163632   

TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163632(SR-3297 | US10807944, Compound RLS2-219 | US117319...)
Affinity DataIC50:  1.08E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163632(SR-3297 | US10807944, Compound RLS2-219 | US117319...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) using acetylated 7-amino-4-methylcoumarin (AMC) as peptide substrate measured after 20 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163632(SR-3297 | US10807944, Compound RLS2-219 | US117319...)
Affinity DataIC50:  1.08E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent